Trump installs Stephen Miller as chief of staff, replacing Susie Wiles

Washington — President Trump announced Friday that Stephen Miller will replace Susie Wiles as White House chief of staff, the most significant shakeup of his team since Republicans' losses in the midterm elections .

Wiles submitted her resignation to the president on Thursday night, a U.S. official and a senior White House adviser told CBS News. Wiles' resignation was tied to Republican midterms defeats, according to three sources familiar with the matter. It was unclear if her deputies would remain at the White House.